Diclofenac Sodium
Reviewed by Dr Bipin B. 
- Drug class: NSAIDs
- Generic name: Diclofenac Sodium
- Brand name: Vovaran, Reactin
Introduction
Diclofenac sodium is a widely used nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed to relieve pain and reduce inflammation in various conditions. The aim of this article is to provide a comprehensive understanding of Diclofenac Sodium including its mechanism of action, therapeutic uses, possible side effects, precautions, and more.
Mechanism of action
Diclofenac sodium works by inhibiting the production of certain enzymes responsible for pain and inflammation in the body. Specifically, it targets cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins, which are responsible for pain, fever, and inflammation.
Uses:-
Diclofenac sodium is widely prescribed for the management of pain and inflammation associated with following conditions:-
arthritis,
osteoarthritis,
rheumatoid arthritis,
ankylosing spondylitis,
gout.
It also effectively treats acute migraine, dysmenorrhea (menstrual pain), and post-traumatic & post-operative pain.
Dosages:
The dosage of diclofenac sodium may vary depending on the condition being treated. It is available in various formulations including tablets, capsules, gels and injections. The recommended dosage and administration instructions should be followed strictly to ensure optimum effectiveness and minimize the risk of side effects.
50 mg twice / thrice a day
75 mg deep im
1% topical gel
Side effects:
While diclofenac sodium is generally well tolerated, it can cause some side effects in some individuals. Common side effects include gastrointestinal issues such as
abdominal pain,
nausea
indigestion
diarrhea.
gastric ulceration and bleeding are less common.
CNS effects might occurs like
headache
dizziness
Skin reactions such as rash or itching may also occur.
kidney damage might occur and is rare.
It is important to report any serious or persistent side effects to a health care professional right away.
Precaution and contraindication
Certain precautions must be taken while using diclofenac sodium. Individuals with a history of stomach ulcers, gastrointestinal bleeding, kidney problems, liver disease, or heart diseases should avoid it or use it with caution. The use of diclofenac sodium is contraindicated in patients with known hypersensitivity to NSAIDs or aspirin.
Drug interaction
Diclofenac sodium may interact with other medications, including
some blood thinners,
diuretics,
antidepressants.
To avoid potential drug interactions that may affect the safety and efficacy of diclofenac sodium, it is essential to inform healthcare providers about all current medications, including over-the-counter medications and supplements.
Overdose and its treatment
In case of an overdose of Diclofenac Sodium, immediate medical help should be sought. Overdose symptoms may include
severe stomach pain,
nausea,
vomiting,
drowsiness,
difficulty breathing.
Emergency measures may include gastric lavage, administration of activated charcoal, and supportive care to manage symptoms.
Diclofenac substitutes
While diclofenac sodium is an effective medication for pain and inflammation, alternative treatment options are also available. These options may include other NSAIDs, such as ibuprofen or naproxen, as well as non-pharmacological approaches such as physical therapy, hot or cold therapy, and lifestyle modifications. It is important to discuss options with a health care professional to determine the option best suited for individual needs.
conclusion
Diclofenac sodium is a widely prescribed NSAID that provides relief from pain and inflammation associated with various conditions. It is important to understand its mechanism of action, therapeutic uses, possible side effects, precautions, and drug interactions for safe and effective use. By following recommended dosages, being aware of potential side effects, and consulting with healthcare professionals, individuals can make informed decisions regarding the use of diclofenac sodium for their specific needs. Remember to always seek professional medical advice before starting or stopping any medication.
yes, but it is recommended to take it on empty stomach.
it takes 20-30 min to start working.
Diclofenac sodium is not recommended in pregnancy as it affects baby’s circulation and decrease amniotic fluid however it is safe in breastfeeding.
Omega 3 EFAs found in fish reduces inflammatory process.
yes, it can be used for chronic pain condition till no side effects is seen.
take it as soon as you remember however do not double it if your next dose time has already reached.
Diclofenac may cause dizziness, so driving and operating machinery should be avoided.
it is used for chronic condition like arthritis. you can take this medicine for long time under supervision of healthcare worker.
Diclofenac tablets, capsule and suppositories are safe for children aged 6 month and above.
No, but it can irritate stomach. so, drinking too much alcohol should be avoided.
Voveran SR 100 belongs to a group of drugs called non-steroidal anti-inflammatory drugs, which is used to treat muscle pain, toothache, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, arthritis, and inflammation.
Reactin plus is a combination medicine which has Diclofenac and paracetamol as ingredient and being used to treat muscle pain, toothache, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, arthritis, and inflammation.
Voveran is used for alleviating pain and swelling in joints affected by degenerative arthritis, autoimmune disorders, or gout; easing pain stemming from illness, headaches, backaches, or dental issues; and relieving pain in various body parts due to muscle sprains, fractures, dislocations, or tendon ruptures.
Voveran 50 MG Tablet alleviates pain, stiffness, and swelling in joints associated with rheumatoid arthritis, osteoarthritis, gout, and ankylosing spondylitis. It also aids in relieving pain after dental surgery, operations, and surgical procedures, as well as pain arising from minor injuries.
Voveran Emulgel Gel is a nonsteroidal anti-inflammatory drug (NSAID) used to treat neck, shoulder, back, muscle, knee, joint, and sprain pain. Its active ingredient is diclofenac sodium. It is advisable to consult your doctor before applying the gel.
Voltaren alleviates pain and diminishes inflammation (swelling and redness) associated with various conditions, including arthritis like rheumatoid arthritis and osteoarthritis. It also effectively addresses other painful needs where swelling is a concern, such as back pain, rheumatism, muscle strains, sprains, and tendonitis.
Voltaren gel alleviates back pain, knee pain strains, shoulder pain, hip pain strains, or joint pain. It targets explicitly relieving pain, inflammation, and swelling associated with soft-tissue injuries or trauma affecting tendons, ligaments, muscles, and joints.
One Cataflam sugar-coated tablet contains 50 mg of diclofenac potassium.